Too much of a good thing? Oxygen and asthma

A summary of a Randomised controlled trial comparing high concentration oxygen to titrated oxygen in acute severe asthma. What was the point?  There is an increasing body of evidence that high levels of oxygen may be harmful administered for a prolonged period in several circumstances including stroke, MI and Emergency surgery. Studies are being undertaken in the paediatric population.  This study was interesting as focused on short term condition associated with immediate mortality from hypoxia- Acute severe Asthma. How was it done?  A Randomised controlled multi-centre trial.   Where and on whom was it done?  3 New Zealand Emergency departments Adults 18-65 years old Diagnosis of both previous and acute asthma with…